Senior Research Fellow Area: Bioinformatics EmailID:firstname.lastname@example.org Affiliation: Department of Genetic Engineering, Kattankulathur Campus, SRM Institute of Science and Technology, (formerly known as SRM University)
Pursuing at SRM Institute of Science and Technology (formerly known as SRM University)
SRM Institute of Science and Technology (formerly known as SRM University), 2014
Tamil Nadu Agricultural University, 2012
Screening of large virtual compound libraries
Molecular dynamics simulation
Quantitative Structure Activity Relationship Study
Sathya B, Santhosh Kumar N, and Thirumurthy M (2019). Investigation of Empirical and Semi‐Empirical Charges to Study the Effects of Partial Charges on Quality and Prediction Accuracy in 3D‐QSAR. Chemistry Select, vol. 4, pp.3990 –4002.
Sathya B, Santhosh Kumar N, and Thirumurthy M (2019). Understanding the structural features of JAK2 inhibitors: a combined 3D-QSAR, DFT and molecular dynamics study. Mol Diversity.
Santhosh Kumar N, Sathya B, Sohn H, Panneer D, and Thirumurthy M (2018). Towards a better understanding of the interaction between Somatostatin receptor 2 (SSTR2) and its ligands: a structural characterization study using molecular dynamics and conceptual Density Functional Theory (DFT). Journal of Biomolecular Structure and Dynamics, vol. 17, pp.1-22.
Santhosh Kumar N, Sathya B, and Thirumurthy M (2017). Theoretical analysis of somatostatin receptor 5 with antagonists and agonists for the treatment of neuroendocrine tumors. Molecular Diversity, vol. 21(2), pp.367-384.
Santhosh Kumar N, Sathya B, Sohn H, Panneer D, and Thirumurthy M (2017). 3D-QSAR studies on indole and 7-azoindole derivatives as ROCK-2 inhibitors: An integrative computational approach. Computational Biology and Chemistry, vol. 71, pp.104-116.
Sathya B, Rupa M, Santhosh Kumar N, Sohn H, and Thirumurthy M (2016). Molecular Modeling Study on Diazine Indole Acetic Acid Derivatives for CRTH2 Inhibitory Activity. Combinatorial Chemistry & High Throughput Screening, vol. 19(6), pp.444-460.
Sathya B, Santhosh Kumar N, Hang Lee S, and Thirumurthy M (2016). Structural characterization of human CRTh2: a combined homology modeling, molecular docking and 3D-QSAR-based in silico approach. Medicinal Chemistry Research, vol. 25(4), pp.653-671.
Sathya B, Kulkarni S.A, Sohn H and Thirumurthy M (2015). Identification of leads through insilico approaches utilizing benzylthio-1H-benzo[d]imidazol-1yl acetic acid derivatives: A potent CRTh2 antagonist. Journal of Molecular Structure, vol. 1102, pp. 25-41.
Sathya B, Sohn H, and Thirumurthy M (2015). Computational analysis of CRTH2 receptor antagonist: A Ligand- based CoMFA and CoMSIA approach. Computational Biology and Chemistry, vol. 56, pp. 109-121.
Sathya B, Akila Parvathy D, Ramesh Kumar G (2015). NGS Meta data analysis for identification of SNP and INDEL patterns in human airway transcriptome: A preliminary indicator for lung cancer, Applied & Translational Genomics, vol.4, pp. 4-9.
Work in Progress
Identifying the potent lead compounds for Janus Kinase enzymes (JAK).
Optimizing the available JAK inhibitors using Quantitative Structure Activity Relationship Study.