Dr.N. Manoj Kumar, Ph.D

Assistant professor (Sr.G.)
Area: Bioprocess technology, Bioseparation engineering and Pharmacogenomics
Phone Number:  91-44-27417817
Affiliation: Department of Genetic Engineering, Kattankulathur Campus, SRM Institute of Science and Technology (formerly known as SRM University).
Email: manojkun@srmist.edu.in

Other Details:

Courses

• Bioprocess Engineering
• Biochemical Engineering
• Bioseparation Technology
• Pharmacogenomics and Personalized Medicine
• Bioinstrumentation
• Molecular Medicine
• Genes and Diseases
• Enzyme Engineering

Research Interests

• Production of Therapeutic enzyme using microbial source.
• Phamacogenetics of antidiabetic drugs
• Analysis of Antioxidant and Anticancer activities of marine algal extracts

        Selected Publications:

• C. Muthukumaran, B.R. Kanmani, G. Sharmila, N. Manoj Kumar, M. Shanmugaprakash, “Carboxymethylation of pectin: Optimization, characterization and in-vitro drug release studies”, Carbohydrate Polymers 194 (2018) 311–318. (I.F : 5.158).
• G. Sharmila , R. Sakthi Pradeep, K. Sandiya, S. Santhiya, C. Muthukumaran, J. Jeyanthi,  N. Manoj Kumar, M. Thirumarimurugan,  “Biogenic synthesis of CuO nanoparticles using Bauhinia tomentosa leaves extract: Characterization and its antibacterial application”, Journal of Molecular Structure 1165 (2018) 288-292.  (I.F : 2.011)
• Kevin Kumar V., Rajnish K.N., Muthukumaran C. and Manojkumar N.* “Computational and functional analysis of an alkaline serine kinase gene (aprn) from the genome of Bacillus subtilis Nrrl - B -14196” Research Journal of Biotechnology, (2018), 13 (2), 64 – 67. (I.F : 0.203)
• Manoj Kumar Narasimhan, Selvarajan Ethiraj, Tamilarasan Krishnamurthi, Mathur Rajesh. “Purification, biochemical and thermal properties of fibrinolytic enzyme secreted by Bacillus cereus SRM-001”. Preparative Biochemistry & Biotechnology, (2017), 48 (1), 34-42. (I.F : 1.241)
• R Felicia Katherine, Chandrasekaran Muthukumaran, Sharmila Govindasamy, Manoj Kumar Narasimhan, K. Tamilarasan, R. Jaiganesh. Xanthan gum production using jackfruit-seed-powder-based medium: optimization and characterization. “3 Biotech, (2017) 7(4) : 248.
• G. Sharmila, M. Farzana Fathima, S. Haries, S. Geetha, N. Manoj Kumar, C. Muthukumaran Enhanced catalytic and antibacterial activities of phytosynthesized palladium nanoparticles using Santalum album leaf extract. “Journal of Powder Tehnology, 320 (2017) 22-26.
• Chandrasekaran Muthukumaran, Loganathan Banupriya, Somasundharam Harinee, Sivagurunathan Sivaranjani, Govindasamy Sharmila, Vinayagam Rajasekar, Narasimhan Manoj Kumar. “Pectin from muskmelon (Cucumis melo var. reticulatus) peels: extraction optimization and physicochemical properties.” 3 Biotech, (2017) 7:66
• Chandrasekaran Muthukumaran, Ramachandran Praniesh, Periyasamy Navamani,  Raghavan Swathi, Govindasamy Sharmila, Narasimhan Manoj Kumar. “Process optimization and kinetic modeling of biodiesel production using non-edible Madhuca indica oil.” Fuel, 195 (2017) 217–225.
• G. Sharmila, M. Farzana Fathima, S. Haries, S. Geetha, N. Manoj Kumar, C. Muthukumaran. “Green synthesis, characterization and antibacterial efficacy of palladium nanoparticles synthesized using Filicium decipiens leaf extract.” Journal of Molecular Structure (2017), doi: 10.1016/ j.molstruc.2017.02.097.
• G. Sharmila, V.S. Nikitha, S. Ilaiyarasi, K. Dhivya, V. Rajasekar, N. Manoj Kumar, K. Muthukumaran, C. Muthukumaran. “Ultrasound assisted extraction of total phenolics from Cassia auriculata leaves and evaluation of its antioxidant activities” Industrial Crops and Products, 84 (2016) 13–21.
• Manoj Kumar Narasimhan, Muthukumaran Chandrasekaran and Mathur Rajesh. “Fibrinolytic enzyme production by newly isolated Bacillus cereus SRM-001 with enhanced in-vitro blood clot lysis potential.” Journal of  General and Applied Microbiology, 2015, 61, 157–164.
• Manoj Kumar Narasimhan, Shenoy K Pavithra, Vishnupriya Krishnan, Muthukumaran Chandrasekaran. “In vitro Analysis of Antioxidant, Antimicrobial and Antiproliferative Activity
• of Enteromorpha antenna, Enteromorpha linza and Gracilaria corticata Extracts.” Jundishapur Journal of Natural Pharmaceutical Products, 2013, 8(4): 151-9.
• N. Manoj Kumar, S. Karthikeyan , G. Jayaraman “Thermostable alpha-amylase enzyme production from Bacillus laterosporus: Statistical optimization, purification and characterization.” Biocatalysis and Agricultural Biotechnology, 2013, 2:38–44.

Book Chapters

• Narasimhan Manoj Kumar, Chandrasekaran Muthukumaran, Govindasamy Sharmila, Gurunathan Baskar, “Bioremediation Applications for Environmental Protection and Management [Genetically Modified Organisms and Its Impact on the Enhancement of Bioremediation]”, Springer, 978-981-10-7485-1, (2018), 1, Page No : 53-76
• Chandrasekaran Muthukumaran, and Govindasamy Sharmila Narasimhan M Kumar, Arul J Gnanaprakasam, and Vaiyazhipalayam M Sivakumar, “Encyclopedia of Renewable and Sustainable Materials [Optimization and Kinetic Modeling of Biodiesel Production]”, Elsevier, (2018), https://doi.org/10.1016/B978-0-12-813195-4.10578-4. (In Press).

Working Papers

• Cloning and characterization of Fibrinolytic enzyme gene from  Bacillus sp
• Production of pigments from floral extracts and analysis of its antioxidant potential
• Pharmacogenetic aspects of cardiovascular drugs

Work in Progress

• Biogenic synthesis of nanoparticles for therapeutic purpose.
• Anxiolytic drug behavior studies using zebra fish model. 

Academic Experience:

• Assistant Professor , Department of Genetic Engineering, SRM Institute of Science and Technology (formerly known as SRM University), Kattankulattur, India (2007-Till date).

Other Professional Experience:

• Lecturer, Department of industrial Biotechnology, Bharath University  Chennai   2006 – 2007
• Worked in quality analysis and formulation sector in SPIC Health care Pvt. Ltd, At Maraimalainagar, for 1 year.(2006 - 07)

Funded Project:

• N. Manoj Kumar, “Detection of SNPs in SLC22A1 gene in Type 2 Diabetes Mellitus patients undergoing Metformin drug therapy in Indian population.” (2013), Tamilnadu State Council for Science and Technology, India. 

Memberships:

• Member in Indian Science Congress Association (ISCA).
• Member in Indian Society of Human Genetics (ISHG).    

Achievement and Award

• Distinction award in B. Pharm Degree