Dr. K.N .ArulJothi, Ph.D

PDF: University College London, UK; University of Cape Town, South Africa

Assistant Professor (Sr.G)
Area: Genetic Engineering
Affiliation: Department of Genetic Engineering, Kattankulathur Campus, SRM Institute of Science and Technology (formerly known as SRM University)
Email ID: aruljotn@srmist.edu.in

Other Details:

Courses

• Human genetics
• Genes and Diseases
• Diagnosis of Genetic Diseases
• Human Physiology
• Animal cell culture and transgenic Technology
• Molecular Pathology of infectious disease
• Microbiology
• Gene Expression Laboratory
• Molecular Techniques laboratory.

Guideship:     

• PhD Students  : Nil
• M.Tech Students  : 3
• B.Tech Students  : 20

Research Interests

• Human Genetics and Genomics and Molecular Markers
• Cardiovascular diseases

Selected Publication

• Kirubakaran Rangasamy, Murugan Athiappan, Natarajan Devarajan, Javid A. Parray, Nowsheen Shameem, K. N. Aruljothi, Abeer Hashem, Abdulaziz A. Alqarawi, and Elsayed Fathi Abd_Allah Cloning and Expression of the Organophosphate Pesticide-Degrading α-β Hydrolase Gene in Plasmid pMK-07 to Confer Cross-Resistance to Antibiotics,  BioMed Research International Research Article (13 pages), Article ID 1535209, Volume 2018 (Impact factor - 2.58)
• K.N. ArulJothi , Suruthi Abirami B, Devi A: Genetic spectrum of low density lipoprotein receptor gene variations in South Indian population. 2018. Clinica Chimica Acta. Dec 19;478:28-36. doi: 10.1016/j.cca.2017.12.024 (Impact factor- 2.9)
• K.N. ArulJothi, B. Suruthi Abirami, Sivaraj Irusappan, Amarnath Gautami, C. Swathine, A. Devi: L55M and Q192R polymorphism of Paraoxonase gene and the risk of myocardial infarction in South Indian Tamil population, Feb 2018, Meta Gene, Vol. 15, 55 – 59.
• KN. ArulJothi., Nair Sahana , Budamagunta Vivekananda , Meenakshisundaram,  Association of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G and Apolipoprotein E polymorphisms with risk of Myocardial Infarction in Indian Tamil Population. 2018, Research Journal of Biotechnology. 13 (1), 91-98(Impact factor – 0.23)
• Kirubakaran Rangasamy, Murugan Athiappan, Natarajan Devarajan, Gopinath Samykannu, Javid A. Parray, K.N. Aruljothi: Pesticide degrading natural multidrug resistance bacterial flora, 2017, Microbial Pathogenesis, vol. 114, 304-10. (Impact factor – 2.33)
• G Shashikant, KN ArulJothi, A Devi, Recent Advances in Therapeutic Approaches for Familial Hypercholesterolemia. 2017, Genom & Gene Ther Int J 1 ((1))
• K.N. ArulJothi, R.A. Whitthall, M Futema, S.E. Humphries, Melvin George, S Elangovan, Devaki R Nair, A Devi: Molecular analysis of the LDLR gene in coronary artery disease patients from the Indian population. Clinical biochemistry,  03/2016;, DOI:10.1016/j.clinbiochem.2016.02.009 (Impact factor - 2.4)
• K.N. ArulJothi, Irusappan Sivaraj, Suruthi Abirami B, M.K. Harishankar, Devi Arikketh: Extension and Modification of Kanai’s DNA Isolation Method for a Spectrum of Human Specimens Collected by Invasive and Noninvasive Methods Suitable for Genotyping Studies. Biosciences Biotechnology Research Asia 06/2016; 13(2):1075-1082., DOI:10.13005/bbra/2135
• KN ArulJothi, Abinaya M et al, SCARB1 rs5888 c.1050C>T Polymorphism and the Risk of Hypercholesterolemia and Myocardial Infarction in Indian Tamil Population, Pakistan J. Zool., vol. 49(3), DOI: http://dx.doi.org/10.17582/journal.pjz/2017.49 (Impact factor - 0.48)
• KN ArulJothi, Devi. A, Melvin George, S Elangovan, R A Whittall, S E Humphries, “Effect of novel intronic mutation in LDLR gene in the pathogenicity of FH, Abstract published in Indian Journal of Human Genetics supplementary edition.
• M K Harishankar, S Logeshwaran, S Sujeevan, KN Aruljothi, M.A. Dannie, A Devi: Genotoxicity evaluation of Metformin and Glimepiride by Micronucleus assay in exfoliated urothelial cells of Type 2 Diabetes Mellitus patients.Food and Chemical Toxicology 06/2015; 83., DOI:10.1016/j.fct.2015.06.013 (Impact factor – 3.5)
• R Selvakumar, N Arul Jothi, V Jayavignesh, K Karthikaiselvi, Geny Immanual Antony, P.R. Sharmila, S Kavitha, K Swaminathan: As(V) removal using carbonized yeast cells containing silver nanoparticles. Water Research 10/2010; 45(2):583-92., DOI:10.1016/j.watres.2010.09.034 (Impact factor - 5.9)

Book Chapter

• Kavyasudha C*., Macrin D*., KN ArulJothi*, Joseph J.P., Harishankar M.K., Devi A. (2018) Clinical Applications of Induced Pluripotent Stem Cells – Stato Attuale.2018, In: . Advances in Experimental Medicine and Biology. Springer, New York, N, *Equal contribution (Impact factor – 1.8)

Papers Presented:

• KN ArulJothi, Devi. A, Melvin George, S Elangovan, R A Whittall, S E Humphries, “Effect of novel intronic mutation in LDLR gene in the pathogenicity of FH, 2015, Abstract published in Indian Journal of Human Genetics supplementary edition.

Work in Progress:

• Molecular characterization of novel LDLR mutations identified in Familial Hypercholesterolemia patients of South India

Academic Experience

• Teaching Assistant, SRM Institute of Science and Technology (formerly known as SRM University), Chennai (July 2010 - May 2011)

Other Professional Experience

• Visiting Fellow, Underguidance of  - Prof. Steve Humphries, University College London, Institute of Cardiovascular Science, London, United Kingdom
• M.Tech and PhD, Underguidance of  - Dr. Devi Arikketh, SRM Institute of Science and Technology (formerly known as SRM University), Department of Genetic Engineering, Chennai, India
• Research  student, Underguidance of  - Prof. K. Swaminathan, Bharathiar University, Department of Microbial - Biotechnology, Coimbatore, India
• Indian Young Science Fellow, Underguidance of  - Prof. Durga Rao, Indian Institute of Science, Bangalore, India, Rota viral protein expression studies

Workshops /Seminars/Conferences:

• 2014 – International conference on Human Genetics, Ahmedabad
• 2015 – International conference on Human genetics, Mumbai
• 2016 – International conference on Human Genetics, Chennai
• 2017 – “Sarvasastra” by Dr. MGR University, Chennai

Achievements and Awards

• March 2018 “Scientific Excellence – Junior” Icon Award from Biozone Pvt. Ltd
• Scholarship: Qualified CSIR - NET 2010, All India Rank -  149, June 2010
• Scholarship: Qualified GATE 2010 with 94 percentile, February 2010
• Award: Young Science Fellowship, IISc Bangalore, May 2008
• Award: Periyar University Under Graduation 6th Rank Holder, May 2007

Memberships:

• Member in Indian Science Congress Association (ISCA).
• Life time member in Indian Society of Human Genetics(ISHG)