Dr. S. Kirankumar, Ph.D

PDF: Carnegie Institution for Science, USA; University of Sheffield, UK

Associate Professor
Area: Developmental Biology & Zebrafish Disease Models
Email ID: kirankus@srmist.edu.in
Phone Number: 044-27417857
Affiliation: Department of Genetic Engineering, SRM Institute of Science and Technology (formerly known as SRM University)

Education

Other Details

Number of Ph.D. Students Guiding:     3

Courses

• Principles of Genetics
• Research Methodology
• Developmental Genetics (Animal)
• Cancer Genetics

Research Interests

• Cancer cell metabolism
• VHL cancer syndrome
• Neurodegenerative diseases

Selected Publications

• Venkatasubramanian, H., Selvaraj, V., Ramasamy, M. and K. Santhakumar (2018) Effect of fadrozole exposure on socio-reproductive behaviors and neurochemical parameters in Betta splendens. Zebrafish (in press).
• Selvaraj, V., Venkatasubramanian, H., Roychaudhury, A. and K. Santhakumar (2018) Computational analysis of deleterious SNPs of SLC45A2 involved in Oculocutaneous albinism type 4. Gene Reports 12: 248-254.
• Selvaraj, V. and K. Santhakumar  (2017)  Analyzing locomotor activity in zebrafish larvae using wrMTrck. Zebrafish 14: 287-291.
• Kim, H.R., Greenald, D., Vettori, A., Markham, E., Santhakumar, K., Argenton, F. and F. van eeden  (2017)  Zebrafish as a model for von Hippel Lindau and hypoxia-inducible factor signaling. Methods in Cell Biology 138: 497-523.
• Hong, E., Santhakumar, K., Akitake, C.M., Ahn, S.J., Thisse, C., Thisse, B., Wyart, C., Mangin, J-M. and M.E. Halpern  (2013)  Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.  Proceedings of National Academy of Sciences, USA 110: 21171-6.
• Santhakumar, K., Judson, E.C., Elks, P.M., McKee, S., Elworthy, S., van Rooijen, E., Walmsley, S.S., Renshaw, S.A., Cross, S. and F.J.M. van Eeden  (2012)  A zebrafish  model to study and therapeutically manipulate hypoxia signaling in tumorigenesis.   Cancer Research 72: 4017-27
• Snelson, C.D., Santhakumar, K., Halpern, M.E. and J.T. Gamse  (2008)  tbx2b is required for the development of parapineal organ.  Development  135: 1693-1702.
• Kirankumar, S. and T.J. Pandian  (2004)  Interspecific androgenetic restoration of rosy barb using cadaveric sperm.  Genome 47: 66-73.
• Anathy, V., Venugopal, T., Kirankumar, S. and T.J. Pandian  (2004)  Growth enhancement and food conversion efficiency of transgenic fish, Labeo rohita.  Journal of Experimental Zoology, Part A. Comparative Experimental Biology 301: 477-490.
• Kirankumar, S., Anathy, V. and T.J. Pandian  (2003)  Hormonal induction of supermale golden rosy barb and isolation of Y-chromosome-specific molecular markers. General and Comparative Endocrinology 134: 62-71
• Anathy, V., Kirankumar, S. and T.J. Pandian  (2003)  Enhanced expression of b-thymosin mRNA in the ovary of GnRH analog and Estradiol-17b (E2) treated fish, Macropodus opercularis.  Comparative Biochemistry and Physiology: Part A. Molecular and Integrative Physiology 134(3):639-645.

Funded Projects

• Principal Investigator, “A zebrafish model to study hypoxia signaling in tumorigenesis”, SERB, Govt. of India, Rs. 46.09 Lakhs (2018-2021)
• Principal Investigator, “Developing a zebrafish model to characterize SDH-mediated tumorigenesis”, DBT, Govt. of India, Rs. 24.68 Lakhs (2015-2018)
• Principal Investigator, “A zebrafish model to characterize FH-mediated renal cell carcinoma”, SERB, Govt. of India, Rs. 26.00 Lakhs (2015-2018)

Workshops/ Seminars/ Conferences

• Organizer, Workshop on “CRISPR-Cas9 mediated mutagenesis in zebrafish” held at    Department of Genetic Engineering, SRM Institute of Science and Technology (formerly known as SRM University), India during Mar. 3rd, 2017.
• Secretary, “Animal Genetics” module, “Indian Genetics Congress 2015” held at SRM Institute of Science and Technology, India during Mar. 4th-6th, 2015.
• Organizer, Workshop on “Zebrafish Model System: Development and Genetics” held at Department of Genetic Engineering, SRM Institute of Science and Technology (formerly known as SRM University), India during May 12th-13th, 2014.

Academic Experience

• Research Associate, Department of Biomedical Science, The University of Sheffield, Sheffield - S10 2TN, UK.
• Post-Doctoral Fellow, Department of Embryology, Carnegie Institution for Science, Baltimore -MD 21218, USA.

Achievements and Awards

• CRUK Travel Award to attend the 16th ISDB Congress held at Edinburgh, Sep. 2009
• Carnegie Post-doctoral Fellowship from Sep. 2003 to Oct. 2007
• CSIR Senior Research Fellowship from Jul. 2002 to Jul. 2003
• ICAR Junior Research Fellowship from Mar.1998 to Jun. 2002