Dr. M. K. Kathiravan

Professor and Head

Mail ID:kathiravan.k@ktr.srmuniv.ac.in
Area: Pharmaceutical Chemistry 
Affiliation: Department of Pharmaceutical Chemistry, SRM College of Pharmacy SRM Institute of Science and Technology (formerly known as SRM University) Kattankulathur, Chengalpattu Dt - 603 203.

Other Details:

Research Interests

• Design, synthesis of antimicrobials  agents and anticancer agents
• CADD
• Biomaterial synthesis

Selected Publications

• Dendrimers - From organic synthesis to pharmaceutical applications: An update- Pharmaceutical Development and Technology-2015 , 20(1), 22-40
• Design, Synthesis and QSAR Studies on a Series of 2, 5-Disubstituted-1,3,4-oxadiazole Derivatives of Diclofenac and Naproxen For Analgesic and Anti-inflammatory activity Medicinal Chemistry - in press -2015 
• Ion pairing with linoleic acid simultaneously enhances encapsulation efficiency and antibacterial activity  of vancomycin in solid lipid nanoparticles-Colloids and Surfaces B: Biointerfaces, 2014, 117, 303-311
• 3D CoMFA, CoMSIA, topomer CoMFA and HQSAR studies on mono/dihydroxy benzoic esters for carbonic anhydrase inhibitory activity- Journal of Chemometrics, 2014, 28(1), 60-70. 
• Inhibition of glutamine synthetase: A potential drug target in Mycobacterium tuberculosis Molecules 2014, 19, 1-17 
• Mycothiol: A promising antitubercular target- Bioorganic Chemistry, 2014, 52, 62–68 
• The novel dual use of formamide-POCl3 mixture for the efficient, one-pot synthesis of condensed 2H-pyrimidin-4-amine libraries under microwave irradiation - Syn Comm., 2013- 43: 719–727 (0.98)
• Synthesis of novel substituted thieno[3,2-d]pyrimidines as potential antihyperlipidemic agents – Letters in Drug Design and Discovery, 2013, 10, 906-915 
• Synthesis  &  antihyperlipidemic activity of novel condensed  2-fluoromethylpyrimidines
  Med Chem Res 2013, 22, 4286–4292
• Synthesis and biological evaluation of novel condensed pyrimidinylmethylsulfinyl benzimidazoles as antiulcer agent- Med Chem Res 2013, 22, 3719–3727 

Working Papers

• CoMFA, CoMSIA and Hologram QSAR studies on NTF1836 analogues as mycothiol Inhibitors

Work in Progress

• Design, synthesis and biological evaluation of substituted 2-thioxopyrimidine-5-carbonitrile and 1-thioxo-pyrimido[6,1-b]quinazoline-4-carbonitrile as anti tubercular agents Communicated to Journal of Chemical Biology (JOCB-D-15-00022)
• Kathiravan et al  Discovery and development of topoisomerase inhibitors as exciting anticancer agents  Communicated to  Current Topics in Medicinal Chemistry
• Exploring Pyrimidine pharmacophore as Thymidine Monophosphate Kinase inhibitors for antitubercular activity communicated to Current Topics in Medicinal Chemistry

Academic Experience

• Professor in SRM College of Pharmacy, SRM Institute of Science and Technology (formerly known as SRM University) since July 2015
• Professor in Seven Hills College of Pharmacy, JNTU Anantapur, July 2014 to June 2015
• Associate Professor in Sinhgad College of Pharmacy, University of Pune from Feb 2011 to August 2013 
• Assistant Professor AISSMS College of Pharmacy, University of Pune August 2009 to Feb 2011
• Lecturer, Sinhgad College of Pharmacy, University of Pune, Sep 2003 to  April 2004

Other Professional Experience 

• Postdoctoral Fellow, Department of Pharmaceuticals Sciences, UKZN, Durban, August 2013 to April 2014  
• Research Scientist I in Jubilant Chemsys, Noida, Dec 2008 to July 2009
• Research Scientist in Chemtek Laboratories, Pune 2005

Achievements and Awards

• Senior Research Fellow (SRF) from ICMR, New Delhi 2005-2008
• Project Fellow under University Grant Commission, New Delhi 2004-2005     
• Won First prize for the oral paper “A rapid and facile synthesis of α-amino nitrile employing ionic liquid.” Presented at National Conference on “Trends in Pharmaceutical Industry, PHARMEET 2011”, at MITCON Institute of Management, Balewadi, Pune-45, 8th Oct 2011.
• IJPER Award 2008 for Best Article in the field of Pharmaceutical Chemistry: “Methyl benzimidazoles as Potential Reversible Proton Pump Inhibitors” IJPER 2008, Vol. 42 (1), Jan-Mar, 2008, Pp-59-64
• Best Research Project for the year 2005-2006 :
  “Design, Synthesis and Biological Evaluation of Some Novel Cholesterol lowering agents” by 54th IPCT, Pune.
• Best Poster Presentation Award in Medicinal Chemistry :
  “Deign, Synthesis and Evaluation of novel mutual prodrugs of LM 1554 and its active analog with  Vit. B3 for antihyperlipaemic activity” at 57th Indian Pharmaceutical Congress 2005, Hyderabad
• Best Poster Presentation Award in Indigenous Drugs :
  Standardization of herbal formulations containing Andrographis Paniculata” at  54th Indian Pharmaceutical Congress 2002, Pune